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KPV

Also known as: Lysine-Proline-Valine

Anti-inflammatory / GutGrey areaHalf-life: 1h

Overview

KPV is a tripeptide fragment derived from alpha-MSH that is commonly researched for anti-inflammatory activity, particularly in gut, skin, and immune contexts. It is not an approved prescription peptide medicine.

How it works

Associated with melanocortin-related anti-inflammatory signalling. It may reduce NF-kB activation and inflammatory cytokine expression in preclinical models, with research interest in epithelial barrier function, colitis models, and skin inflammation.

Primary uses

  • Anti-inflammatory research
  • Gut barrier research
  • Skin inflammation research
  • Immune modulation
  • Colitis model research

Storage and preparation

Store lyophilised material frozen or refrigerated, protected from light and moisture. Reconstituted material should be refrigerated and used within supplier-validated stability guidance.

Reconstitute with bacteriostatic water, sterile water, or suitable research buffer. Add diluent gently and swirl without shaking.

kpvalpha-msh fragmentanti-inflammatorygutskinimmune

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