Epitalon
Also known as: Epithalon, Epitalone
Overview
Epitalon is a synthetic tetrapeptide based on Epithalamin, a natural polypeptide produced by the pineal gland. It has been extensively studied by Russian researcher Vladimir Khavinson over several decades, with research suggesting telomere-lengthening, anti-ageing, and sleep-regulating properties.
How it works
Stimulates the pineal gland to produce melatonin and regulate circadian rhythms. Activates telomerase enzyme activity, potentially extending telomere length and slowing cellular ageing. Also acts as an antioxidant, reduces oxidative stress, and may restore the function of the hypothalamic-pituitary axis.
Primary uses
- Telomere extension
- Anti-ageing
- Sleep quality improvement
- Antioxidant
- Pineal gland regulation
- Circadian rhythm normalisation
What to expect
Based on reported user experiences and available research, here is a general timeline of effects:
Days 1–7
- Pineal gland stimulation begins — melatonin production may improve within days
- Sleep quality improvements are often reported early
- Store in dark conditions — very light sensitive
Days 7–20
- Telomerase activation is underway — cellular repair mechanisms are engaged
- Antioxidant and anti-inflammatory effects are building
- Circadian rhythm normalisation is progressing
Days 20–999
- You are completing the typical 10-20 day Epitalon cycle
- Rest for 3-6 months before your next cycle
- Long-term telomere length and cellular ageing benefits are the primary goal
Storage and preparation
Store lyophilised at -20°C. Once reconstituted, store at 4°C and use within 20 days. Very sensitive to light — store in dark vials or wrapped in foil.
Reconstitute with bacteriostatic water or sterile saline. Common: 10mg vial with 2ml BAC water gives 5mg/ml. For 5mg dose, draw 1ml. Typically used in cycles of 10-20 days.
Research
The following studies are available via PubMed:
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