AOD-9604
Also known as: Advanced Obesity Drug 9604
Overview
AOD-9604 is a modified fragment of human growth hormone (hGH) spanning amino acids 176-191. It was specifically designed to retain the fat-burning properties of GH without the anabolic or diabetogenic effects. Has received FDA GRAS (Generally Recognised As Safe) status as a food additive.
How it works
Mimics the way natural growth hormone regulates fat metabolism. Stimulates lipolysis (breakdown of fat) and inhibits lipogenesis (fat production) without affecting insulin sensitivity or IGF-1 levels. Acts on beta-3 adrenergic receptors in adipose tissue to promote fat oxidation.
Primary uses
- Fat loss and lipolysis
- Metabolism enhancement
- Cartilage repair
- No effect on blood sugar
What to expect
Based on reported user experiences and available research, here is a general timeline of effects:
Days 1–14
- Lipolysis stimulation begins from the first dose
- Best administered fasted in the morning for optimal fat oxidation
- Some users notice appetite changes in the first week
Days 14–56
- Fat metabolism is measurably elevated by week 3-4
- Localised fat reduction in stubborn areas is progressing
- No IGF-1 or blood sugar impact — safer metabolic profile than full GH
Days 56–999
- Sustained fat loss benefits with consistent use
- Cartilage repair benefits are accumulating alongside fat loss
- Consider combining with a calorie deficit for compounded results
Storage and preparation
Store lyophilised at -20°C or 4°C away from light. Once reconstituted, store at 4°C and use within 14-28 days.
Reconstitute with bacteriostatic water. Common: 5mg vial with 2ml BAC water gives 2500mcg/ml. For 300mcg dose, draw 0.12ml. Best administered fasted in the morning.
Research
The following studies are available via PubMed:
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